DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...

Missed opportunity: PROMs as primary endpoints in bladder cancer trials. This is an ASCO Meeting Abstract from the 2025 ASCO Genitourinary Cancers Symposium. This abstract does not include a full text ...

ADP-ribosylation, the attachment of ADP-ribose to proteins, is a common eukaryotic post-translational modification. It exists in two forms: mono ADP-ribosylation (MARylation), where individual units ...

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...

The researchers focused on Fanconi anemia, a rare inherited disorder characterized by a failure to repair specific types of ...

In a recent study published in the journal Nature, researchers found that the recruitment of neurons to memory circuits is preceded by a cascade of molecular events induced during learning, which ...

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals capable of detecting and responding to physical tension in DNA. This ...